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Oculocutaneous Albinism (Small Breed Type)

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Description:

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Test Overview:

Oculocutaneous Albinism (Small Breed Type) in dogs refers to a genetic condition where affected dogs have a reduced amount of melanin, the pigment responsible for color in the skin, hair, and eyes. This results in a pale or white coat, pinkish skin, and often light blue or pale eyes. Beyond cosmetic differences, albinism can also lead to increased photosensitivity and vision problems in dogs. The "Small Breed Type" distinction implies this form of the mutation is particularly found or has been studied in smaller dog breeds. A genetic test can identify if a dog carries the gene responsible for this type of albinism, helping breeders make informed decisions.

Category:

Trait (Associated with Phenotype)

Gene:

SLC45A2

Variant Detected:

chr4:73867311 (canFam3): G/A

Severity:

It is a trait and so is tested based on preference, not usually for health concerns.

Mode of Inheritance:

Autosomal Recessive with Incomplete Penetrance

Research Citation(s):

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092127

Associated Breed(s):

French Bulldog, Lhasa Apso, Pekingese, Pomeranian,
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