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Canine Multifocal Retinopathy CMR2 (Coton du Tulear Type)*
$50.00 (RRP)
$50.00 (MEMBER PRICE)
Description:
Canine multifocal retinopathy 2 is an inherited disease affecting the retina. Retinal changes are usually present in affected animals before 4 months of age and are characterized by multifocal areas of retinal which in older dogs progress to multifocal areas of outer retinal atrophy. These multifocal areas of retinal are typically found in both eyes and can appear gray, tan, orange or pink and vary in number, size and location.
Vision loss has also been described as the disease progress in older animals.
Category:
Ophthalmologic - Associated with the eyes and associated structures
Gene:
BEST1
Variant Detected:
c.482G>A (CMR2)
Severity:
Low-Moderate. This disease can cause some discomfort and/or dysfunction in the affected animal. It does not generally affect life expectancy.
Mode of Inheritance:
Autosomal Recessive
Research Citation(s):
Invest Ophthalmol Vis Sci. 2007 May;48(5):1959-67